Mannitol vs. HTS in Elevated ICP from Acute CNS Infection
"Randomized Clinical Trial of 20% Mannitol Versus 3% Hypertonic Saline in Children With Raised Intracranial Pressure Due to Acute CNS Infections"
by Ramachandran Rameshkumar et al.
Pediatr Crit Care Med. 2020 Dec;21(12):1071-1080.
Conclusions: In pediatric acute CNS infections, 3%-hypertonic saline was associated with a greater reduction of intracranial pressure as compared to 20% mannitol.
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